G 418, sulfate, SERVA

Opis towaru

G 418, or Geneticin, is a aminoglycoside antibiotic from Micromonospora rhodorangea. The antibiotic is used for the selection and maintenance of eukaryotic cells expressing the neomycin resistance gene (neo). G418 blocks polypeptide synthesis by inhibiting the elongation step. It is similar in structure to gentamycin B1 but active against both bacteria and eukaryotes.
Stock solution: 10 - 50 mg/ml in H₂O or cell culture medium. The working concentration has to be established for every cell type. Bacteria and algae require 5 μg/ml or less while animal cells may require 300 - 500 μg/ml.

Geneticin®, G418
C₂₀H₄₀N₄O₁₀·2H₂SO₄ 

M_r 692.7

CAS No. 108321-42-2

Potency: min. 650 µg/mg

Storage Temperature +15 °C TO +30 °C